| 产品详情 |
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| Antigenic Specificity | Ku80 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, peptide-ELISA: 1:16000, Western Blot: 0.1-0.3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku80 Polyclonal Antibody. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of VJ recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo VJ recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
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| Immunogen | n/a |
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| Other Names | XRCC5; KU80; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining Ku autoantigen, 80kDa) ; HGNC:12833; KARP-1; KARP1; Ku86; NFIV ; ATP-dependent DNA helicase II; DNA repair protein XRCC5; Ku86 autoantigen related protein 1; Ku autoantigen, 80kD; X-ray repair, complementing defective, repair in Chinese hamster |
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| Gene, Accession # | Entrez: 7520; Uniprot: P13010 |
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| Catalog # | PA5-18498 |
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| Price | |
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| Order / More Info | Ku80 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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