| 产品详情 |
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| Antigenic Specificity | Ku80 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Ku80 Polyclonal Antibody. X-ray repair cross-complementing protein 5 (XRCC5), alternative name (Ku80), is a single stranded DNA-dependent ATP-dependent helicase. It is involved in chromosome translocation. Ku80 along with Ku70 forms a heterodimeric protein originally identified as autoantigens, associated with several autoimmune diseases including scleroderma, polymyositis and systemic lupus erythematosus. Ku is a widely expressed nuclear protein that binds to and stabilizes the ends of DNA at telomeres or double-stranded DNA breaks. The inhibition of Ku80 can damage the DNA repair pathway of tumor cells and potentially increase the killing of cancer cells. |
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| Immunogen | n/a |
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| Other Names | KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku autoantigen, 80kDa, Ku86 autoantigen related protein 1, TLAA, X-ray |
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| Gene, Accession # | Entrez: 7520; Uniprot: P13010 |
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| Catalog # | PA5-32472 |
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| Price | |
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| Order / More Info | Ku80 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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