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| Antigenic Specificity | MMS21 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 10 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MMS21 Polyclonal Antibody. MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2. |
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| Immunogen | n/a |
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| Other Names | C8orf36, MMS21, NSE2; E3 SUMO-protein ligase NSE2; MMS21 homolog; hMMS21; methyl methanesulfonate sensitivity gene 21; non-SMC element 2 homolog; non-structural maintenance of chromosomes element 2 homolog |
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| Gene, Accession # | Entrez: 286053; Uniprot: Q96MF7 |
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| Catalog # | A304-128A-T |
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| Price | |
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| Order / More Info | MMS21 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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