| 产品详情 |
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| Antigenic Specificity | eIF6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | eIF6 Polyclonal Antibody. Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity. |
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| Immunogen | n/a |
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| Other Names | Eukaryotic translation initiation factor 6, eIF-6, B(2)GCN homolog, B4 integrin interactor, CAB, p27(BBP), EIF6, EIF3A, ITGB4BP, OK/SW-cl.27 |
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| Gene, Accession # | Entrez: 16418, 305506, 3692; Uniprot: O55135, P56537, Q3KRD8 |
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| Catalog # | PA5-37371 |
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| Price | |
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| Order / More Info | eIF6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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