| Edit |   |
|---|
| Antigenic Specificity | eIF2a |
|---|
| Clone | 5A5 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, nonhuman primate, rat |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:20-1:200, Immunofluorescence: 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | eIF2a Monoclonal Antibody (5A5). EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange. |
|---|
| Immunogen | n/a |
|---|
| Other Names | EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A |
|---|
| Gene, Accession # | Entrez: 1965, 54318; Uniprot: P05198, P68101 |
|---|
| Catalog # | MA1-079 |
|---|
| Price | |
|---|
| Order / More Info | eIF2a Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 27338255, 27658027 |
|---|