| 产品详情 |
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| Antigenic Specificity | eIF2a |
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| Clone | EIF2-alpha |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | eIF2a Monoclonal Antibody (EIF2-alpha). EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange. |
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| Immunogen | n/a |
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| Other Names | EIF-2, EIF2S1, EIF-2alpha, EIF2, EIF2A, eIF-2-alpha, eukaryotic translation initiation factor 2 subunit 1, eukaryotic translation initiation factor 2 subunit alpha |
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| Gene, Accession # | Entrez: 13665, 1965, 54318; Uniprot: P05198, P68101, Q6ZWX6 |
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| Catalog # | AHO0802 |
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| Price | |
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| Order / More Info | eIF2a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11997520, 15623514, 15721356, 15994764, 17429445, 18206657, 24846185, 25774599, 27252530, 27640355, 27852836 |
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