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| Product Name | Cholera Toxin, B Subunit (Choleragenoid) (FITC) Not for Export |
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| Description | The transferase activity of this lot was nearly zero when compared to a comparable amount of cholera toxin standard in an ADP-ribosylation assay. This preparation migrates as a single major band in disc gel electrophoresis under nondenaturing conditions. The R280/260 of each preparation is reported. Cholera toxin is an oligomeric protein of MW 84kD and consists of a single A subunit surrounded by five B subunits. It is a potent activator of adenylate cyclase and is the pathogenic agent responsible for the symptoms of cholera. The B subunit (choleragenoid) is responsible for the binding of the holotoxin to G M1 ganglioside receptors on mammalian cell surfaces and facilitates entrance of the A subunit into the cell. The A subunit bears the ADP-ribosyl-transferase activity, which deregulates the G sprotein causing activation of adenylate cyclase. Due to the ubiquitous occurrence of the GM1 ganglioside receptor on eukaryotic cell membranes, cholera toxin activates adenylate cyclase in a wi |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C4275-36D |
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| Order / More Info | Cholera Toxin, B Subunit (Choleragenoid) (FITC) Not for Export from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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