| 产品详情 |
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| Antigenic Specificity | CD46 |
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| Clone | 8E2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD46 Monoclonal Antibody (8E2), PE, eBioscience™. CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa. |
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| Immunogen | n/a |
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| Other Names | AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10 |
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| Gene, Accession # | Entrez: 4179; Uniprot: P15529 |
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| Catalog # | 12-0469-42 |
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| Price | |
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| Order / More Info | CD46 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 23482486, 28531150 |
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| 产品资料 |
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