| 产品详情 |
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| Product Name | Butaprost |
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| Description | Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle.{3178,1752} Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, TP, FP, or IP receptors.{6640} The EC50 for the stimulation of cAMP by butaprost in COS cells transfected with the human EP2 receptor is about 5 µM, while the EC50 for PGE2 in this assay is about 43 nM.{3178} Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells.{3317} |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester|TR 4979 |
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| Gene, Accession, CAS # | CAS: 69685-22-9 |
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| Catalog # | 13740-5 |
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| Order / More Info | Butaprost from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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