| 产品详情 |
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| Product Name | Oridonin |
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| Description | A diterpenoid with anti-inflammatory and anticancer properties; an inhibitor of AKT1 and AKT2 (IC50s = 8.4 and 8.9 µM, respectively); inhibits proliferation of KYSE70, KYSE410, and KYSE450 esophageal cancer cells, halts the cell cycle at the G2/M phase, and induces apoptosis at 20 µM; decreases the protein levels of phosphorylated AKT and reduces AKT activity; reduces tumor growth in patient-derived mouse tumor models at 40 and 160 mg/kg; an inhibitor of NLRP3 inflammasome assembly and activation; inhibits inflammation in wild-type, but not Nlrp3-/-, mice in a model of high-fat diet-induced type 2 diabetes at 3 mg/kg |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC 250682 |
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| Gene, Accession, CAS # | CAS: 28957-04-2 |
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| Catalog # | 25665-5 |
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| Price | |
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| Order / More Info | Oridonin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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