| 产品详情 |
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| Antigenic Specificity | MTA2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, nonhuman primate |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:1000, Immunofluorescence: 1:1000, Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MTA2 Polyclonal Antibody. MTA2, a homologue of human MTA1 and MTA3, is a member of highly conserved MTA gene family. It is a component of NuRD, an ATP-dependent nucleosome remodeling and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependant transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of Estrogen receptor-alpha. Northern Blot analysis detected a ubiquitous expression of MTA2. |
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| Immunogen | n/a |
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| Other Names | DKFZp686F2281, MTA1L1, PID |
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| Gene, Accession # | Entrez: 9219; Uniprot: O94776 |
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| Catalog # | PA1-41581 |
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| Price | |
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| Order / More Info | MTA2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25247294 |
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