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| Antigenic Specificity | Absent in Melanoma 2 (AIM2) (aa 1-186) |
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| Clone | 3B10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | supernatant |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AIM2 is a strong candidate as a tumor suppressor as it is a member of the HIN-200 (hemopoietic interferon-inducible, nuclear proteins containing a 200 amino acid repeat) family of proteins that have been shown to regulate cell growth and survival. The HIN-200 family of proteins consists of four members in human, IFI 16 [8], MNDA [9], AIM2 [1] and IFIXl. Recently it has been reported that AIM2 is a receptor for cytosolic dsDNA, which forms a novel inflammasome complex with ASC to activate caspase-1-mediated processing of IL-1beta. |
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| Immunogen | Human AIM2 (aa 1-186). |
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| Other Names | AIM2|PYHIN4|Gm1313|Ifi210 |
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| Gene, Accession # | Gene ID: 9447 |
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| Catalog # | ABIN1169341 |
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| Price | |
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| Order / More Info | Absent in Melanoma 2 (AIM2) (aa 1-186) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15582594, 19158675, 19158676 |
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