| 产品详情 |
| Edit |   |
| Antigenic Specificity | PIKFYVE |
| Clone | OTI1A5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100 µl |
| Concentration | n/a |
| Applications | Immunohistochemistry (Paraffin): 1:2000, Western Blot: 1:2000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PIKFYVE Monoclonal Antibody (OTI1A5). PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva. |
| Immunogen | n/a |
| Other Names | 1-phosphatidylinositol 3-phosphate 5-kinase ; Phosphatidylinositol 3-phosphate 5-kinase; FYVE finger-containing phosphoinositide kinase; PIKfyve; Phosphatidylinositol 3-phosphate 5-kinase type III; PIPkin-III; Type III PIP kinase |
| Gene, Accession # | Entrez: 200576; Uniprot: Q9Y2I7 |
| Catalog # | MA5-27291 |
| Price | |
| Order / More Info | PIKFYVE Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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