| 产品详情 |
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| Antigenic Specificity | MSL1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MSL1 Polyclonal Antibody. Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation. |
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| Immunogen | n/a |
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| Other Names | Male-specific lethal 1 homolog, MSL-1, Male-specific lethal 1-like 1, MSL1-like 1, Male-specific lethal-1 homolog 1, MSL1, MSL1L1 |
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| Gene, Accession # | Entrez: 339287; Uniprot: Q68DK7 |
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| Catalog # | PA5-54608 |
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| Price | |
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| Order / More Info | MSL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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