| 产品详情 |
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| Product Name | Geldanamycin |
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| Description | Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells. Purity 98%. MW (observed): 560.64 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-carbamate |
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| Gene, Accession, CAS # | Gene ID: 3320, CAS: 30562-34-6 |
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| Catalog # | 1368/1 |
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| Price | |
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| Order / More Info | Geldanamycin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 16504968, 25700737, 26627605 |
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| 产品资料 |
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