| 产品详情 |
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| Antigenic Specificity | LSM11 |
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| Clone | OTI7F12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LSM11 Monoclonal Antibody (OTI7F12). LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
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| Immunogen | n/a |
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| Other Names | 2210404M20Rik, LSM11 homolog, U7 small nuclear RNA associated, U7 snRNA-associated Sm-like protein LSm11 |
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| Gene, Accession # | Entrez: 134353; Uniprot: P83369 |
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| Catalog # | MA5-27248 |
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| Price | |
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| Order / More Info | LSM11 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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