| 产品详情 |
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| Antigenic Specificity | MINA53 |
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| Clone | M532 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay Dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry: Assay Dependent, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MINA53 Monoclonal Antibody (M532). MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. |
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| Immunogen | n/a |
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| Other Names | MDIG, MINA53, NO52, MYC-induced nuclear antigen, mineral dust induced gene protein, mineral dust-induced gene protein, myc-induced nuclear antigen, 53 kDa, nucleolar protein 52 |
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| Gene, Accession # | Entrez: 84864; Uniprot: Q8IUF8 |
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| Catalog # | 39-7300 |
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| Price | |
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| Order / More Info | MINA53 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 14695334, 19561615, 24324617 |
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