| 产品详情 |
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| Antigenic Specificity | MINA53 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MINA53 Polyclonal Antibody. MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias. |
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| Immunogen | n/a |
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| Other Names | MDIG, MINA53, NO52; MYC-induced nuclear antigen; mineral dust induced gene protein; mineral dust-induced gene protein; myc-induced nuclear antigen, 53 kDa; nucleolar protein 52 |
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| Gene, Accession # | Entrez: 67014, 84864; Uniprot: Q8CD15, Q8IUF8 |
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| Catalog # | PA5-20909 |
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| Price | |
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| Order / More Info | MINA53 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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