| 产品详情 |
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| Antigenic Specificity | Dclre1c/Artemis |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Dclre1c/Artemis Polyclonal Antibody. Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5' to 3' exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5' and 3' overhangs and hairpins. |
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| Immunogen | n/a |
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| Other Names | ASCID, DCLRE1C DNA cross link repair 1C, DCLRE1C protein, DCLREC1C, DNA cross link repair 1C, FLJ11360, RS SCID, SCIDA, Severe combined immunodeficien |
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| Gene, Accession # | Entrez: 227525; Uniprot: Q8K4J0 |
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| Catalog # | A304-902A |
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| Price | |
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| Order / More Info | Dclre1c/Artemis Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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