| 产品详情 |
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| Antigenic Specificity | CH25H |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 200 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CH25H Polyclonal Antibody. Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiat |
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| Immunogen | n/a |
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| Other Names | Cholesterol 25-hydroxylase; 1.14.99.38; Cholesterol 25-monooxygenase; h25OH; CH25H |
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| Gene, Accession # | Entrez: 12642, 9023; Uniprot: O95992, Q9Z0F5 |
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| Catalog # | PA5-72349 |
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| Price | |
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| Order / More Info | CH25H Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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