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| Antigenic Specificity | PMEL |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | peptide-ELISA: 1:128000, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PMEL Polyclonal Antibody. This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript var |
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| Immunogen | n/a |
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| Other Names | silver homolog (mouse) ; PMEL17; SILV ; D12S53E; ME20; SI; SIL; gp100 ; Melanocyte protein mel 17; Pmel 17; Silver, mouse, homolog of; silver (mouse homolog) like; silver (mouse homolog)-like; silver homolog |
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| Gene, Accession # | Entrez: 6490; Uniprot: P40967 |
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| Catalog # | PA5-18538 |
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| Price | |
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| Order / More Info | PMEL Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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