| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | MKP-1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 400 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western Blot: 1:1000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MKP-1 Polyclonal Antibody. The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts |
|---|
| Immunogen | n/a |
|---|
| Other Names | Dual specificity protein phosphatase 1, MAP kinase phosphatase-1, MKP-1, Protein-tyrosine phosphatase CL100, Dual specificity protein phosphatase hVH1, CL100, MKP1, PTPN10, VH1 |
|---|
| Gene, Accession # | Entrez: 1843; Uniprot: P28562 |
|---|
| Catalog # | PA5-15593 |
|---|
| Price | |
|---|
| Order / More Info | MKP-1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|