| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | 16G6 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1-4 µg/mL, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (16G6), eBioscience™. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death |
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| Immunogen | n/a |
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| Other Names | GrB |
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| Gene, Accession # | Entrez: 14939; Uniprot: P04187 |
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| Catalog # | 14-8822-80 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18202224, 19786545, 20156973, 20213736, 20956344, 21860023, 22036949, 22072975, 22251703, 25015830, 25502180 |
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