| 产品详情 |
| Edit |   |
| Antigenic Specificity | Granzyme B |
| Clone | NGZB |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, kappa |
| Format | APC-eFluor 780 conjugate |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry: 0.25 µg/test |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Granzyme B Monoclonal Antibody (NGZB), APC-eFluor 780, eBioscience™. Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which func |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | Entrez: 14939; Uniprot: P04187 |
| Catalog # | 47-8898-82 |
| Price | |
| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
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