| 产品详情 |
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| Antigenic Specificity | Granzyme B |
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| Clone | O2C5/F5 |
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| Host Species | Mouse |
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| Reactive Species | human, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 1 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme B Monoclonal Antibody (O2C5/F5). Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells. Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells. Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells. The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Gra |
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| Immunogen | n/a |
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| Other Names | GrB |
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| Gene, Accession # | Entrez: 171528, 3002; Uniprot: P10144, P18291 |
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| Catalog # | MA1-26455 |
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| Price | |
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| Order / More Info | Granzyme B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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