| 产品详情 |
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| Antigenic Specificity | Granzyme K |
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| Clone | GM24C3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1:200-1:400, Flow Cytometry: 1.2 µg/1x10^6 cells |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Granzyme K Monoclonal Antibody (GM24C3). Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes. |
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| Immunogen | n/a |
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| Other Names | GrK |
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| Gene, Accession # | Entrez: 3003; Uniprot: P49863 |
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| Catalog # | MA1-17753 |
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| Price | |
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| Order / More Info | Granzyme K Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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