| 产品详情 |
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| Antigenic Specificity | CARD8 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CARD8 Polyclonal Antibody. The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. |
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| Immunogen | n/a |
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| Other Names | CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN, CARD inhibitor of NF-kappaB-activating ligands, apoptotic protein NDPP1, caspase recruitment domain-containing protein 8, tumor up-regulated CARD-containing antagonist of CASP9, tumor up-regulated CARD-containing antagonist of caspase nine |
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| Gene, Accession # | Entrez: 22900; Uniprot: Q9Y2G2 |
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| Catalog # | PA5-27695 |
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| Price | |
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| Order / More Info | CARD8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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