| 产品详情 |
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| Antigenic Specificity | Na+ CP- Pan |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Na+ CP- Pan Polyclonal Antibody. Scn10a is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Scn10a mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, Scn10a forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Scn10a also plays a role in neuropathic pain mechanisms. Structurally, members of Deg/ENaC superfamily of ion channels share organizational similarity in that they all possess two short |
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| Immunogen | n/a |
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| Other Names | SCN2A, NAC2, SCN2A1, SCN2A2, Nav1.1, NAC1, SCN1, SCN1A, Nav1.2, SCN3A, KIAA1356, NAC3, Nav1.3, Nav1.4, SCN4A, Nav1.5, SCN5A, Nav1.6, SCN8A, MED, Nav1.7, SCN9A, NENA, Nav1.8, SCN10A, Nav1.9, hNaN, SCN11A, SCN12A, SNS2 |
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| Gene, Accession # | Entrez: 110876, 110880, 11280, 20264, 20265, 20269, 20271, 20273, 20274, 24046, 24766, 25665, 25722, 29571, 29701, 29710, 497770, 6323, 6326, 6328, 6329, 6331, 6334, 6335, 6336, 78956, 81574; Uniprot: A2APX8, O08562, O88420, O88457, P04774, P04775, P08104, P15389, P15390, P35498, P35499, Q14524, Q15858, Q62205, Q62968, Q6QIY3, Q99250, Q9ER60, Q9JJV9, Q9NY46, Q9R053, Q9UI33, Q9UQD0, Q9WTU3, Q9Y5Y9 |
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| Catalog # | PA5-36074 |
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| Price | |
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| Order / More Info | Na+ CP- Pan Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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