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Product Name | Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3 (PELI3) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 54.8kDa. Full Length: 1-469aa. N-terminal 6xHis-tagged. Homo sapiens (Human). E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | RING-type E3 ubiquitin transferase pellino homolog 3 (Pellino-3) |
Gene, Accession, CAS # | PELI3, UniProt: Q8N2H9 |
Catalog # | RPC26199 |
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Order / More Info | Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3 (PELI3) from BIOMATIK |
Product Specific References | n/a |
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