| 产品详情 |
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| Antigenic Specificity | Phospho-IP3 Receptor 1 (Ser1588, Ser1598) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100, peptide-ELISA: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IP3 Receptor 1 (Ser1588, Ser1598) Polyclonal Antibody. Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. |
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| Immunogen | n/a |
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| Other Names | Inositol 1,4,5,-Triphosphate Receptor Type I, IP3R, IP3R1 |
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| Gene, Accession # | Entrez: 16438, 25262, 3708; Uniprot: P11881, P29994, Q14643 |
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| Catalog # | PA5-38628 |
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| Price | |
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| Order / More Info | Phospho-IP3 Receptor 1 (Ser1588, Ser1598) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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