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| Antigenic Specificity | Synaptotagmin 1 |
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| Clone | 8G11B10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1/500 - 1/2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Synaptotagmin 1 Monoclonal Antibody (8G11B10). Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane. It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Further, Synaptotagmin 1 binds acidic phosphol |
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| Immunogen | n/a |
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| Other Names | P65; SYT; SVP65; DKFZp781D2042; SYT1 |
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| Gene, Accession # | Entrez: 6857; Uniprot: P21579 |
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| Catalog # | MA5-15466 |
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| Price | |
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| Order / More Info | Synaptotagmin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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