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| Antigenic Specificity | Synaptotagmin 1 |
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| Clone | ASV48 |
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| Host Species | Mouse |
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| Reactive Species | bovine, mouse, nonhuman primate, rat, shark |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 0.1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Synaptotagmin 1 Monoclonal Antibody (ASV48). Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane. It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size. Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Further, Synaptotagmin 1 binds acidic phospholip |
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| Immunogen | n/a |
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| Other Names | Syb1 |
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| Gene, Accession # | Entrez: 20979, 25716, 281511, 6857; Uniprot: P21579, P21707, P46096, P48018 |
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| Catalog # | MA1-25482 |
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| Price | |
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| Order / More Info | Synaptotagmin 1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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