| 产品详情 |
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| Antigenic Specificity | WSB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | WSB1 Polyclonal Antibody. WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis. |
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| Immunogen | n/a |
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| Other Names | WD repeat and SOCS box-containing protein 1; WSB-1; SOCS box-containing WD protein SWiP-1; WSB1; SWIP1 |
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| Gene, Accession # | Entrez: 26118, 303336, 78889; Uniprot: O54927, Q9Y6I7 |
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| Catalog # | PA5-75162 |
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| Price | |
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| Order / More Info | WSB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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