| 产品详情 |
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| Antigenic Specificity | MLH1 |
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| Clone | Clone 14 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 9-11 µg/mL, Western Blot: 1-1.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLH1 Monoclonal Antibody (Clone 14). This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. |
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| Immunogen | n/a |
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| Other Names | COCA2, FCC2, HNPCC, HNPCC2, MGC5172, hMLH1 |
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| Gene, Accession # | Entrez: 4292; Uniprot: P40692 |
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| Catalog # | MA1-90218 |
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| Price | |
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| Order / More Info | MLH1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 17943475, 18202787, 18705767, 18949393, 19275958, 19464205, 19567531, 19821155, 26067142 |
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