| 产品详情 |
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| Antigenic Specificity | CD11a |
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| Clone | TS1/22 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 200 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD11a Monoclonal Antibody (TS1/22). CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. CD11a is thus invo |
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| Immunogen | n/a |
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| Other Names | CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L |
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| Gene, Accession # | Entrez: 16408, 3683; Uniprot: P20701, P24063 |
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| Catalog # | MA11A10 |
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| Price | |
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| Order / More Info | CD11a Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10626904, 10670580, 12032326, 12426210, 12798306, 12885870, 15265939, 15294914, 15470064, 15944315, 16009719, 16116327, 16458321, 16720640, 16990435, 17114441, 17596165, 17888931, 18190605, 19587009, 24088571, 27055590, 3028646, 3594570, 6196430, 8558021, 8648124, 9551935, 9786897 |
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