| 产品详情 |
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| Antigenic Specificity | E2F1 |
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| Clone | KH95 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Gel Shift: 1mg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:100, Immunoprecipitation: 2 µg/mg protein lysate, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | E2F1 Monoclonal Antibody (KH95). E2F's are DNA-binding proteins that associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F-1 also requires DP-1 for efficient DNA-binding and transcription modification. E2F1 is proposed to be involved in several cellular processes that range from tumor suppression, cell cycle progression, and oncogenesis. E2F-1 overexpression can also drive cells into apoptosis. These observations place E2F among a group of apoptosis inducers that includes; c-Myc, Adenovirus E1A, and HPV E7 protein. |
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| Immunogen | n/a |
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| Other Names | PBR3, PRB-binding protein E2F-1, RBAP-1, RBBP-3, retinoblastoma-associated protein 1, retinoblastoma-binding protein 3, transcription factor E2F1 |
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| Gene, Accession # | Entrez: 13555, 1869; Uniprot: Q01094, Q61501 |
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| Catalog # | MA5-14344 |
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| Price | |
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| Order / More Info | E2F1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11297263, 15307143, 17989570, 18006809, 18172256, 19076682, 22179774, 22688350, 22751436, 24936870 |
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