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| Product Name | Lactate Dehydrogenase (LDH) Cytotoxicity Assay Kit, BioAssay™ |
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| Description | Lactate Dehydrogenase (LDH) is an oxidoreductase which catalyzes the interconversion of lactate and pyruvate. Cytotoxic compounds often compromise cell membrane integrity by inducing apoptosis or necrosis. LDH is a stable cytosolic enzyme that upon membrane damage is released into the cellular environment. Therefore, LDH is often measured to evaluate the presence of tissue or cell damage. The colorimetric LDH release assay is a simple and robust method to assess cytotoxic effects on cells by measuring the activity of LDH in cell culture supernatant. The assay is based on the reduction of the tetrazolium salt MTT to a formazan dye which exhibits an absorption maximum at 565 nm. Key Features: Safe. Non-radioactive assay (cf. chromium release assay). Fast. High-throughput assay using 96-well plates allows simultaneous processing tens of thousands of samples per day. Homogeneous and convenient. Mix-incubate-measure type assay. No wash steps are involved. Robust and amenable to HTS. Can b |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1013-98 |
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| Order / More Info | Lactate Dehydrogenase (LDH) Cytotoxicity Assay Kit, BioAssay™ from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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