| 产品详情 |
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| Antigenic Specificity | Phospho-IRS1 (Ser636, Ser639) |
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| Clone | 25HCLC |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-IRS1 (Ser636, Ser639) Antibody (25HCLC), ABfinity™ Rabbit Oligoclonal. IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4). IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues. An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo. Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II. Thus, casein kinase II-catalyzed phosphorylat |
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| Immunogen | n/a |
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| Other Names | HIRS-1 |
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| Gene, Accession # | Entrez: 3667; Uniprot: P35568 |
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| Catalog # | 710781 |
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| Price | |
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| Order / More Info | Phospho-IRS1 (Ser636, Ser639) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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