| 产品详情 |
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| Antigenic Specificity | Phospho-JAK1 (Tyr1022) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-JAK1 (Tyr1022) Polyclonal Antibody. Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, |
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| Immunogen | n/a |
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| Other Names | EC 2.7.10.2, JAK-1, JAK1, JAK1A, Janus kinase 1, kinase Jak1 |
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| Gene, Accession # | Entrez: 16451, 3716, 84598; Uniprot: P23458, P52332 |
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| Catalog # | PA5-37617 |
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| Price | |
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| Order / More Info | Phospho-JAK1 (Tyr1022) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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