| 产品详情 |
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| Antigenic Specificity | NALP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP2 Polyclonal Antibody. NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1-b-processing activity and is thought to function as a modulator of NF-kappa-B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternati |
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| Immunogen | n/a |
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| Other Names | CLR19.9, NALP2, NBS1, PAN1, PYPAF2; NACHT, LRR and PYD containing protein 2; NACHT, LRR and PYD domains-containing protein 2; NACHT, leucine rich repeat and PYD containing 2; PYRIN domain and NACHT domain-containing protein 1; PYRIN-containing APAF1-like protein 2; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2; nucleotide-binding site protein 1 |
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| Gene, Accession # | Entrez: 232827, 55655, 684545; Uniprot: Q9NX02 |
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| Catalog # | PA5-20213 |
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| Price | |
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| Order / More Info | NALP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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