| 产品详情 |
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| Antigenic Specificity | NALP4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP4 Polyclonal Antibody. NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-kappa-B induction by TNF-a and IL-1-b, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-kappa-B induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TR |
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| Immunogen | n/a |
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| Other Names | CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2; NACHT, LRR and PYD containing protein 4; NACHT, LRR and PYD domains-containing protein 4; NACHT, leucine rich repeat and PYD containing 4; PAAD and NACHT-containing protein 2; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; cancer/testis antigen 58; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4; ribonuclease inhibitor 2 |
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| Gene, Accession # | Entrez: 147945, 243880; Uniprot: Q8BU40, Q96MN2 |
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| Catalog # | PA5-21020 |
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| Price | |
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| Order / More Info | NALP4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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