| 产品详情 |
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| Antigenic Specificity | NALP5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 10 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP5 Polyclonal Antibody. NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders. |
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| Immunogen | n/a |
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| Other Names | CLR19.8, MATER, NALP5, PAN11, PYPAF8; NACHT, LRR and PYD domains-containing protein 5; NACHT, leucine rich repeat and PYD containing 5; mater protein homolog; maternal antigen that embryos require; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 |
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| Gene, Accession # | Entrez: 126206, 23968, 308325; Uniprot: P59047, Q9R1M5 |
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| Catalog # | PA5-21021 |
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| Price | |
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| Order / More Info | NALP5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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