| 产品详情 |
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| Antigenic Specificity | NALP7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 10 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NALP7 Polyclonal Antibody. NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1-b secretion and is a feedback regulator of interleukin-1-b secretion. Defects in the NALP7 gene are known to cause the formation of a hydat |
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| Immunogen | n/a |
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| Other Names | CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3; NACHT, LRR and PYD containing protein 7; NACHT, LRR and PYD domains-containing protein 7; NACHT, leucine rich repeat and PYD containing 7; PYRIN-containing Apaf1-like protein 3; nucleotide-binding oligomerization domain protein 12; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7 |
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| Gene, Accession # | Entrez: 199713; Uniprot: Q8WX94 |
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| Catalog # | PA5-21023 |
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| Price | |
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| Order / More Info | NALP7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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