| 产品详情 |
| Edit |   |
| Antigenic Specificity | TYROBP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TYROBP Polyclonal Antibody. This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative rec |
| Immunogen | n/a |
| Other Names | DAP12, KARAP, PLOSL, DNAX-activation protein 12, KAR-associated protein, TYRO protein tyrosine kinase-binding protein, killer activating receptor associated protein, killer-activating receptor-associated protein |
| Gene, Accession # | Entrez: 7305; Uniprot: O43914 |
| Catalog # | PA5-28803 |
| Price | |
| Order / More Info | TYROBP Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |
| 产品资料 |
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