| 产品详情 |
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| Antigenic Specificity | WTAP |
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| Clone | OTI12G7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | WTAP Monoclonal Antibody (OTI12G7). Wilms' tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and is observed in both sporadic and inherited forms. The Wilms' tumor protein (WT1) binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators, and functions as a transcriptional repressor. WTAP (Wilms tumor 1-associating protein) is a ubiquitously expressed nuclear protein that interacts with WT1 and may be involved in regulating mRNA splicing. WTAP is found in nuclear speckles, where it regulates the G2/M cell cycle transition by binding to the 3' UTR of cyclin A2, thus enhancing its stability. Additionally, WTAP inhibits exp |
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| Immunogen | n/a |
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| Other Names | PNAS-132, WT1-associated protein, Wilms' tumour 1-associating protein, female-lethal(2)D homolog, hFL(2)D, pre-mRNA-splicing regulator WTAP, putative pre-mRNA splicing regulator female-lethal(2D), wilms tumor 1-associating protein |
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| Gene, Accession # | Entrez: 9589; Uniprot: Q15007 |
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| Catalog # | MA5-26972 |
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| Price | |
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| Order / More Info | WTAP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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