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Product Name | Δ12-Prostaglandin D2 |
Description | PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. .DELTA.12-PGD2 is one of the initial chemical decomposition products of PGD2. .DELTA.12-PGD2 is an intermediate in the pathway leading to .DELTA.12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities.{870,334} The metabolism of .DELTA.12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.{7193} |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | Δ12-PGD2 |
Gene, Accession, CAS # | CAS: 64072-89-5 |
Catalog # | 12650-500 |
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Order / More Info | Δ12-Prostaglandin D2 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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