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| Product Name | Deltarasin (hydrochloride) |
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| Description | A small molecule that binds to the farnesyl-binding pocket of PDEδ (Kd = 41 nM) in cells thus inhibiting its interaction with KRAS and disrupting RAS signaling; reduces proliferation and increases cell death of Panc-Tu-I tumor cells at 5 µM in a human pancreatic ductal adenocarcinoma cell model; reduces tumor growth at a dose of 10 mg/kg in nude mice xenografted with pancreatic carcinoma |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1440898-82-7 1440898-61-2 KRAS oncogene PDEδ PDE.delta. PDEdelta PDEd PDE δ .delta. delta d inhibitors inhibits inhibitions RAS pancreatic cancers cells signaling signals RAS humans pancreatic pancreas ductal adenocarcinoma Panc-Tu-I tumors mice mouse carcinoma xenografts intracellular transduction HCl |
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| Gene, Accession, CAS # | CAS: 1440898-82-7 |
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| Catalog # | 9001536-1 |
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| Price | |
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| Order / More Info | Deltarasin (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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