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| Antigenic Specificity | TrxR2 |
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| Clone | 25B3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA: Assay dependent, Immunoprecipitation: 1-2 µL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TrxR2 Monoclonal Antibody (25B3). The mammalian thioredoxin reductases (TrxRs) are a family of selenocysteine-containing pyridine nucleotide-disulfide oxidoreductases. All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate selenocysteine (SeCys) residue in the conserved sequence (-Gly-Cys-SeCys-Gly). TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site. Electrons are transferred from NADPH via FAD and the active-site disulfide to C-terminal SeCys-containing r |
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| Immunogen | n/a |
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| Other Names | trxR2 |
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| Gene, Accession # | Entrez: 10587; Uniprot: Q9NNW7 |
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| Catalog # | LF-MA0054 |
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| Price | |
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| Order / More Info | TrxR2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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