| 产品详情 |
| Edit |   |
|---|
| Product Name | HAV-VP1-P2A protein |
|---|
| Description | HAV-VP1-P2A (residues 669-782) protein.The protein contains the HAV Coat protein VP1 and coreprotein P2A immunodominant regions, amino acids 669-782.HAV core proteins are purified by proprietary chromatographic techniques.Forty-two antigenic domains were identified across thehepatitis A virus (HAV) polyprotein by using a set of 237overlapping 20-mer synthetic peptides spanning the entire HAV polyprotein and a panel of serum samples fromacutely HAVinfected patients. The term antigenic domainis used in this study to define a protein regionspanned with consecutivefiverlapping immunoreactivepeptides.Nineteen antigenic domains were found within the structural proteins, and 22 were found within the nonstructuralproteins, with 1 domain spanning the junction of VP1 andP2A proteins. Five of these domains were considered immunodominant, as judged by both the breadth and thestrength of their immunoreactivity. One domain is locatedwithin the VP2 protein at position 57-90 aa. A seconddomain, located at position 767-842 aa, contains the Cterminal part of the VP1 protein and the entire P2A protein. A third domain, located at position 1403-1456 aa,comprises the C-terminal part of the P2C protein and theN-terminal half of the P3A protein. The fourth domain,located at position 1500-1519 aa, includes almost theentire P3B, and the last domain, located at position 1719-1764 aa, contains the C-terminal region of the P3C protein and the N-terminal region of the P3D protein. It is interesting to note that four of thefive most immunoreactivedomains are derived from small HAV proteins and/or encompass protein cleavage sites separating different HAVproteins. Purity >90% by SDS-PAGE |
|---|
| Size | 1 mg, 100 ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA, WB |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | orb97861 |
|---|
| Price | |
|---|
| Order / More Info | HAV-VP1-P2A protein from BIORBYT LTD. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|