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Product Name | Pyridostatin pentahydrochloride |
Description | Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs). Purity 98%. MW (observed): 778.94 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride |
Gene, Accession, CAS # | CAS: 1781882-65-2 |
Catalog # | 4763/50 |
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Order / More Info | Pyridostatin pentahydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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